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Menopause + hormones

HRT online. Menopause care first.

  • Hot flashes, sleep and more
  • Licensed U.S. clinicians
  • Check-ins and refills included

No payment to start · Prescription only if a licensed clinician decides it’s right for you

Compounded, not FDA-approved. Hormone therapy can raise the risk of blood clots, stroke and some cancers, depending on your age, health and the type you use. Safety information

Illustrative packaging: a hormone cream pump beside its carton on a travertine plinth against a soft studio background. Your medicine is labeled and dispensed by the licensed pharmacy.

Menopause first

Care that starts with your symptoms.

The options

Whole-body or local.

Where the hormone goes shapes what it treats. Your clinician matches the type to your symptoms and your risks, and explains non-hormonal options too.

What changed in 2026. The FDA asked companies to take statements about cardiovascular disease, breast cancer and probable dementia out of the boxed warning on menopausal hormone therapy labels, and approved the first updated labels on February 12, 2026.

The boxed warning about endometrial cancer stays for whole-body estrogen used alone, and cardiovascular disease and breast cancer risks are still in the labels’ warnings. Your own risks depend on your age, health and the type you use.

Is it for you?

Who HRT may suit, and who it isn’t for.

May suit you if

  • Hot flashes or night sweats bother you
  • You’re within 10 years of menopause, or under 60
  • Vaginal dryness or pain with sex is your main concern (local therapy)

Not for you if

  • You’ve had breast or endometrial (uterine) cancer
  • You’ve had a stroke, a heart attack, blood clots or other heart disease
  • You have liver disease or unexplained vaginal bleeding
  • You are pregnant

Needs a closer look

  • Starting more than 10 years after menopause, or after 60
  • Gallbladder disease
  • Every medicine and supplement you take

From ACOG and The Menopause Society. Whole-body hormone therapy is the usual concern on these lists; local therapy has far lower risks. A licensed clinician makes the final decision.

How it works

Four steps. All online.

  1. Step 1

    Share your story

    Your symptom timeline, cycle history, medicines and goals.

  2. Step 2

    Clinician review

    A licensed clinician reviews your risks and explains hormonal and non-hormonal options.

  3. Step 3

    Delivered

    If it’s prescribed, your medicine ships in the form your clinician chose, with instructions.

  4. Step 4

    Check-ins

    Over the first weeks and at month 3: relief, any bleeding and side effects, and whether to adjust.

Pricing

Priced by what you use.

Price shown before you buy

  • Check-ins with your clinician
  • Refills
  • Your medicine, if prescribed

Have a Gabriel wellness budget? Members can use it to pay for this treatment. Learn about Everdawn and Gabriel

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Compounded medications aren’t FDA-approved. A licensed clinician decides what’s right for you. Everdawn’s options are compounded. FDA-approved estradiol and progesterone products also exist, and your clinician explains the difference. Shipping, tax and your full total are confirmed before you pay.

Hormone replacement therapy for menopause, explained (opens in a new tab)

Questions.

How does HRT online work?

You share your symptoms, cycle history, medicines and goals online. A licensed clinician reviews your risks and explains hormonal and non-hormonal options. If hormone therapy is prescribed, it ships to your door, and you check in about relief, bleeding and side effects.

Is compounded hormone therapy safer than FDA-approved hormones?

No. The Menopause Society says custom-compounded hormones are not safer or more effective than approved bioidentical hormones, and ACOG recommends FDA-approved hormone therapy over compounded versions when FDA-approved products exist. Everdawn’s estradiol and progesterone are compounded, and your clinician explains both.

Did the FDA remove the warning on hormone therapy?

In part. The FDA asked companies to remove statements about cardiovascular disease, breast cancer and probable dementia from the boxed warning on menopausal hormone therapy labels, and approved the first updated labels in February 2026. The boxed warning about endometrial cancer stays for whole-body estrogen-alone products, and cardiovascular disease and breast cancer risks remain in the labels’ warnings.

I still have a uterus. What changes?

If you use whole-body estrogen and still have a uterus, you also need a progestogen, such as progesterone. ACOG explains that it helps lower the risk of uterine cancer that estrogen alone can cause.

What if vaginal dryness is my main symptom?

Local vaginal therapy may be enough. The Menopause Society notes very little of it enters the bloodstream, so its risks are far lower.

Is this for men too?

This page is about menopause care. For men with low testosterone, see TRT online. TRT online

Talk through your symptoms.

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Important safety information

Hormone therapy is prescription only and needs an individual risk review.

Boxed warning

  • Estrogen used alone raises the risk of endometrial (uterine) cancer if you have a uterus, which is why a progestogen is added. Report any unusual vaginal bleeding.

Not for you if

  • You’ve had breast or endometrial cancer
  • You’ve had a stroke, heart attack, blood clots or other heart disease
  • You have liver disease or unexplained vaginal bleeding
  • You are pregnant

Risks to understand

  • A small risk of blood clots and stroke, which rises with age and other conditions. Patches, sprays and rings may carry less risk than pills
  • A small increased risk of gallbladder disease
  • Breast cancer risk usually doesn’t rise until after about 5 years of estrogen plus progestogen, or about 7 years of estrogen alone

Most common side effects

  • Headache
  • Breast pain or tenderness
  • Irregular vaginal bleeding or spotting
  • Stomach cramps, bloating or nausea
  • Drowsiness or dizziness, which is why it’s often taken at bedtime

Compounded medications aren’t FDA-approved. A licensed clinician decides what’s right for you. A prescription requires a medical evaluation. Not a complete list: your clinician reviews your history before prescribing. Get prompt medical care for new bleeding, chest pain, sudden shortness of breath, one-sided weakness or a severe new headache. For emergencies, call 911. ACOG: hormone therapy for menopause · FDA labels for estradiol on DailyMed · FDA labels for progesterone on DailyMed

Sources

. General information, not medical advice: a licensed clinician decides what’s right for you.

  1. The Menopause Society: Hormone therapy
  2. ACOG: Hormone therapy for menopause
  3. FDA: Labeling changes approved for menopausal hormone therapy products (February 12, 2026)
  4. FDA consumer update: Hormone replacement therapies for bothersome menopausal symptoms
  5. ACOG: Compounded bioidentical menopausal hormone therapy (2023)
  6. FDA: Compounding and the FDA, questions and answers
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